Abstract # 1001 Upfront Salivaryglandulopexy [A Novel Option to Improve Radiation Compliance & QOL] in Patients Undergoing Radical Radiation Therapy for H & N Cancer

Presenter: Bhalavat, Rajendra

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Mean salivary output of transferred (T) and Untransferred (UT) SMSGD by suction/spit method before and after surgery were equivalent, however the same after RT at 6 months respectively was 1.38ml & 0.12 ml and was statistically significant (p=0.000). Mean output using spit method was 13.2ml (all/4 SGDs) before RT was 3ml post RT [1/SMSGD (T)]. Quantity and quality of saliva was found to be practically normal in 53% at 20Gy deteriorated with increasing dose, was thick and sticky and reduced in 78% at the end of treatment(>/=60Gy). Xerostomia, none to acceptable at 20Gy progressed to grade II / III in 50 % by the end of RT; recovered (grade I) in 78% by 6 months post radiation; was negligible to acceptable by the end of year. There was continual improvement in amount and quality of saliva [comparable to, that of post surgery] post RT reflected with decreased in the intensity of xerostomia improvement in swallowing to nearly normal by 1 year.

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